Saturday 16 April 2016

New Polio Vaccine

I read today on the BBC news site that a new polio vaccine is being pushed out to a waiting world. Here is the article in its entirety:


Vaccine switched in 'milestone'
towards ending polio

Health correspondent, BBC News 
More than 150 countries have begun switching to a different polio vaccine - an important milestone towards polio eradication, health campaigners say. The new vaccine will target the two remaining strains of the virus under a switchover 18 months in the planning.There were just 74 cases of the paralysing disease in 2015 and there have been 10 so far this year. All of the cases were in Afghanistan and Pakistan. Africa has been free of polio for more than a year. 
Switching the vaccine from one successfully used to fight polio for more than 30 years is a huge logistical exercise. Thousands of people will monitor the changeover in 155 countries during the next fortnight.It is taking effect mainly in developing countries, but also in richer ones such as Russia and Mexico. 
The new vaccine will still be given as drops in the mouth, so healthcare workers will not need fresh training. It will no longer include a weakened version of type 2 polio virus, which was eradicated in 1999.
Dr Stephen Cochi, from the US-based Centers for Disease Control (CDC), said: "The current vaccine contains live weakened virus relating to three types of polio. "But we don't need the type 2 component, as it's not in the world any longer. "And in very rare cases it can mutate and lead to polio, through what's called circulating vaccine-derived virus. "So removing type 2 from the vaccine takes away that risk - and ensures we have a vaccine which will work better dose by dose." 
Polio, or poliomyelitis, mainly affects children aged under fiveIt is a highly infectious disease caused by a virus. It invades the nervous system and can cause total paralysis in a matter of hoursInitial symptoms include fever, fatigue, headache, vomiting, stiffness of the neck and pains in the limbs. One in 200 infections leads to irreversible paralysis. Among those paralysed, 5% to 10% die when their breathing muscles become immobilised Today, only two countries - Afghanistan and Pakistan - remain polio-endemic, down from more than 125 in 1988. Source: World Health Organisation 
The planning involved in the switchover has included dealing with a global stockpile of 100 million doses of vaccine targeting just type 2, built up as an insurance policy in case of any outbreak. The World Health Organization denied some media reports that "millions" of doses of the old vaccine would need to be destroyed, by incineration or other approved means. Its director of polio eradication, Michel Zaffran, said: "Some will need to be destroyed - but this will be a few vials, not trucks full of vaccine. "This has been carefully planned because of the huge amount of resources, so countries have been using up the old vaccine, to minimise leftover quantities. "We're closer than ever to ending polio worldwide, which is why we are able to move forward with the largest and fastest globally synchronised vaccine switchover."
In a remarkable admission, the CDC doctor admits that the previously used vaccine could cause polio. He says: But we don't need the type 2 component, as it's not in the world any longer. And in very rare cases it can mutate and lead to polio, through what's called circulating vaccine-derived virus. So removing type 2 from the vaccine takes away that risk - and ensures we have a vaccine which will work better dose by dose." 

In very rare cases it can mutate and lead to polio? Polio itself is very rare: 74 cases in a world population of over 7 billion people. Is the chance of mutation less than this? If a mutation that led to cancer occurred in only one out of a million people, that would mean 7000 cases worldwide if everyone was inoculated. However, no quantitative estimate is given and so we just don't know.

However, we can be consoled by the fact that the other types of live virus don't carry the possibility of this mutation. Yeah, sure. Note that the viruses are not inactivated but live and are being rolled out to developing countries but also richer ones such as Mexico and Russia. This huge, logistical exercise is being carried out for a disease which infected just 74 persons in 2015? Is there more to this rollout? Is this the beginning of the implementation of the global depopulation agenda? 

Another article that appeared in the Medical press states that WHO has warned that the live polio virus used in some vaccines is one of the biggest obstacles to eradicating the disease. It is the trivalent vaccine that is being referred to here and the reason for the change to the new bivalent vaccine seems to be that the former has been responsible for the actual spread of polio via faecal-contaminated water.

Meanwhile, I came across this excellent video on YouTube about the polio vaccine. The video is two years old but in it the creator warns about the very problem that WHO has now admitted to.