Thursday 18 February 2021

How the Pfizer/BioNTech and Moderna Vaccines Work

I've included here a good description of how the Pfizer/BioNTech and Moderna mRNA "vaccines" work. It's taken from an article in Signs of the Times (sott.net) on 30th January 2021.

The technique that was used to produce the Moderna vaccine is the same that was used producing the Pfizer/BioNTech vaccine. A piece of messenger RNA (mRNA) encoding the spike protein of the SARS-CoV-2 virus is inserted into a fat globule made of nanoparticles. Nanoparticles come in many shapes and forms and are made among others from fats, proteins, polymers, metals, silica and carbon. The term "nano" refers to the size of the particles and says nothing about the material used. For use in medicine, nanoparticles are available that are made of polymers, proteins and fats.

In the specific case of Pfizer/BioNTech's and Moderna's mRNA vaccines, the nanoparticle is a fat globule that serves as packaging of the mRNA. This allows the mRNA to pass the barrier of the cell membrane of the body's own cells. In this way, the mRNA is delivered to the cell where it can do its job. The nanoparticle is composed of fatty acids - phospholipids - which organise themselves in the form of a sphere so that the nanoparticles are soluble in water. These phospholipids form the outer layer demonstrated in the illustration below. Another fatty acid with a positive charge binds and protects the mRNA and these are visible as light blue spheres in the illustration. A third component of the fat globule is cholesterol, which stabilises the fat globule. A final component of these nanoparticles is the polyethylene glycol (PEG), which extends the half-life of the fat globule, making it less likely to disintegrate. Animal studies have actually shown that these nanoparticles have another important function as "packaging materials": they cause different types of immune system cells to travel to the injection site.

There are several types of polyethylene glycol, designated by a number such as PEG2000 or PEG3350. This number indicates the molecular weight of the PEG used. Polyethylene glycol PEG2000 is used in both the Pfizer/BioNTech and the Moderna vaccines. It is strongly suspected that this component has caused anaphylactic reactions in susceptible individuals. The risk of an anaphylactic reaction to vaccination with the mRNA vaccines is not known precisely, however it is estimated that for every 100,000 people that are vaccinated with the Pfizer/BioNTech vaccine, 1 will have an anaphylactic reaction. This probability is about 10x higher than it would be for classical vaccines. Therefore, the Centers for Disease Control (CDC) advise people who previously had an anaphylactic reaction to any of the components of these mRNA vaccines to not be allowed to get the vaccine. The problem, however, is that people often don't know, and in addition, at least one case of anaphylaxis was reported in a 32-year-old Alaskan woman who was not aware that she had any type of allergy.

We will now come to the mRNA in the vaccine. This is the "active" component of the vaccine. The purpose of a vaccine based on the mRNA technique is that instead of the body's own cells producing proteins, now the mRNA takes over this production of proteins for a period of time so that it is able to create the virus' spike protein, putting this on its own membrane, just as the virus has this spike protein on its membrane. The next question is which cells will take up this fat globule containing the mRNA and eventually express it. A study using rhesus monkeys shows that mainly antigen-presenting cells take up the nanoparticles and express the mRNA. This occurs at the injection site and in the lymph nodes into which the injection site drains. Antigen-presenting cells are normally immune system cells that cut foreign proteins into small pieces (peptides) and present them to the immune system on top of a small turret (MHC complex), enabling B cells and T cells to examine them in order to assess whether they are the body's own or foreign pieces of protein. If the B and T cells recognise these peptides as foreign to the body, the immune system is activated. To what extent other body cells take up the mRNA vaccine as well and possibly express the mRNA is not well known, but animal research with macaques indicates uptake and expression in muscle cells around the injection site.

Several promotional materials claim that the mRNA in Pfizer/BioNTech's vaccine is identical to the body's own mRNA, and could for that reason alone have no adverse effects. That is not entirely accurate. The mRNA in both vaccines is modified in various ways so that it is more stable and less likely to degrade. Moreover, the different codons - the sequence of three consecutive building blocks in the mRNA - are optimised to maximise the ability of cells to produce the spike protein. In this way, the spike protein is able to express for a longer duration in the body's own cells while producing more spike protein. The aim is to elicit a maximum immune response. As far as is known there have been no adverse effects of these mRNA modifications in humans, however, experience with these techniques in humans is still very limited.

It's important to understand how the vaccine is supposed to work but at the same time it's important to avoid getting caught up further in the whole Covid hype. It's always important to get back to basics and, at base, this is manufactured crisis. Take away the WHO pronouncements, the RT-PCR tests and the media-driven hysteria and 2020 would have been no different to 2019. The recent publicity given to Long-Covid and new mutant strains of the virus are clearly intended to maintain and even heighten the fear factor. The scamdemic is driven by fear.

Image modified from this source

The fear and the stresses of lockdowns, job losses, enforced isolation, business failures etc. are taking a psychological toll that is affecting our physical health. The mask wearing is physically damaging as well by promoting bacterial pneumonia and other illnesses. It is indeed a war on humanity:


There is no doubt that the vaccines will sicken recipients even further but there is no stopping the stampede to get vaccinated. To use Australia as an example, there are already over three million adults and at least one hundred thousand under-18s on antidepressants. These chemically lobotomised people have already surrendered control of their mental health to BIG PHARMA and so they will line up unquestioningly to receive their Covid vaccine. However, even those with a clear head, have succumbed to the relentless propaganda. 

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